Indications: For the treatment of mixed cestode and nematode or arthropod infestations in horses. The blowing parasites of horses are sensitive to the antiparasitic effects of Eqvalan duo, oral paste: Adult Tapeworms: Anopkxephala pe/tbfcrto. large strongytes: Sfrmgy/us vulqam (adults and arterial larval stages), Strongylus edentate (adults and tissue larval stages), Stmngykis equmus (adults), Tnodontophorus spp. (adults), Jnodontophonf. brewoudo, Triodontophonx serrafus, Craterosiomm oaitkaudatum (adults). Adult and mmature fmtraluminal fourth-stage larvae) of small strongytes or cvathostomes, including bemimidaiole-resistant strains: Corontxydus spp., CoronocydiK coronatus, Coronocydus (ohoftB, Coronocydus labratus, Cyathostonwm spp, Cyottmtomum (atmatum, Cyathostomum pateratum, Cyticocydus spp., Cytkocvdus ashworthi, Cytkocydus ehngatus, Cytkocydw msigne, Cybcocydus leptostomum, Cylkocydus nassatus, CylicoaontophonK spp, Cyfcodontophonn bicomatK, CyfaKtephaniG spp, Cytkostephanus calicatvs, Cylkostephanus goldi, CylkostepnaniK lonqibunatw, Cylicostephonus minutus, Parapoterkstomm spp, Porapotenostomum mettam, Petmvinema spp., Petmmetna ppculatum, Poteriostomm spp. Adult hairworms: TridnslrongyliK and. AduH and immature (fourth-stage larvae) pmrorms: Oxyuris equi Adult, third- and fourth-stage larvae of roundwonns (ascarids): Paraxaris equorum. Mkrofilariae of neck threadworms: Onchocerca spp. AduH intestinal threadworms: Strongyloides westeri. Adult large-mouth stomach worms: Habmnema muscae. Oral and gastric stages of bob: Gasterophilus spp. AduH and immature (inhibited fourth stage larvae) tungworms: Dictyocaulus amfteldi.

Overdose: No undesirable effects related to treatmetn were observed in 5months old horses reated with Eqvlan Duo.

Oral paste at up to five times the recommended dose and in adult horses treated at ten times the recommended dose. Transient decreased food consumption, increased body temperature, salivation and impairment of vision were noticed in horses treated twice with an ivermedin oral paste or once with Eqvalan duo, oral paste at ten times the recommended dose (ie, 2 mg/kg b.w.). All changes disappeared within five days. No antidote has been identified; however, symptomatic therapy may be beneficial.

Directions for use: Eqvalan duo, oral paste is for oral administration only. While holding the plunger, turn the knurled ring on the plunger V turn to the left and slide it so the stop ring is at the prescribed weight marking. Lock the ring in place by turning it V4 turn to the right in order to bring the two arrows, the one visible on the ring and the one o the plunger rod, into alignment Make sure the horse's mouth contains no feed. Remove the cover from the tip of the syringe. Insert the syringe tip into the horse's mouth at the interdental space and deposit the paste on the base of the tongue. Immediately raise the horse's head for a few seconds after dosing and ensure that the paste is consumed. Parasite control programme: Veterinary advice should be given on appropriate dosing programmes and stock. Special warnings for nan target spews: The product has been formulated for use in horses only. Cats, dogs, especially collies, old English sheepdogs and related breeds or crosses, and also turtles and tortoises may be adversely affected by the concentration of ivermectin in this product if they are allowed to ingest spilled paste or have access to used syringes. Withdrawal period: Meat 30 days. Do not use in mares producing milk for human consumption. Special precautions to be taken by the person administrating the product to animals: Wash hands after use Do not smoke, drink or eat while handling the product. This product may cause skin and eye irritation. Therefore, the user should avoid contact of the product with the skin and the eyes. In the case of contact rinse immediately with plenty of water. In the case of accidental ingestion or eye irritation after contact seek medical advice immediately and show the label to the physician. For animal treatment only. Disposal advice: Extremely dangerous for fish and aquatic life. Do not contaminate surface water; or ditches product or used syringes. Dispose of any unused product and empty syringes in accordance with guidance from your local waste regulation authority.

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Special precautions in storage: Store in the original container. Replace the rap after use Part used syringes can be kept for up to 2 yean after tret use but staid be used by the expiry date printed below. Keep out of the reach of children. Special precautions for use: Safety studies were not conducted in foals younger than 5 months of age, or in stallions, the use of Eqvalan duo, oral paste is not recommended in these categories of animals. Parasite resistance to any particular class of anthelmintk may develop following frequent repeated use of an anthelminlc of that class. Undesirable effects, frequency and seriousness: Some horses with heavy infections of Ondiocerca spp. mkrofilariae have experienced oedema and pruritis following treatment; such reactions were assumed to be the result of the death of large numbers of mkrofilariae. These signs resolve within a few days but symptomatic treatment may be advisable. In cases of heavy infestations with tapeworms, signs of mild, transient colic and diarrhea may be observed. There have been rare reports of swelling and irritation of the mouth, lip and tongue, and of salivation following administration of Eqvalan duo. These reactions have been transitory in nature, appearing within I hour and abating within 24 to 48 hours following administration.
Use during pregnancy and lactation: Studies performed in laboratory animals showed no teratogenk or embryo toxic effect of either ivermedin or praziquantel at the recommended doses during therapy. The safety of the veterinary medicinal product has not been established during pregnancy and lactation. Use only according to risk/benefit analysis by the responsible veterinary surgeon. Interaction with other medicaments and other forms of interaction: No data available. Dosage, method of administration and advice on correct administration: The recommended dosage is 200 meg ivermedin per kilogram of bodyweight and 1 mg praziquantel per kilogram of bodyweight corresponding to 1.29 g of paste per 100kg bodyweight in a single administration. Bodyweight and dosage should be accurately determined prior to treatment. Die contents of oni syringe Hill treat horses up to 600 kg. Calibrated marking are provided at 100 kg bodyweight intervals. The syringe should be adjusted to the calculated dosage by setting the ring on the appropriate place on the plunger.

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